Que.

The mechanism of action of Paclitaxel is.

  • A. Bind to DNA trhough intercalation between specific bases and block the synthesis of new RNA or DNA, cause DNA strand scission
  • B. Mitotic spindle poison through hte enhancement of tubulin polymerization
  • C. Competitive partial agonist of inhibitor of estrogen and binds to estrogen receptors
  • D. S-Phase specific animetabolite that is converted by deoxykinase to the 5 mononucleotide

Right Answer is :
✓ B. Mitotic spindle poison through hte enhancement of tubulin polymerization
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